Microtubule associated protein 1 light chain 3 beta pseudogene (GS1-279B7.1)

GS1-279B7.1, also named "microtubule associated protein 1 light chain 3 beta pseudogene," is a human pseudogene, meaning it resembles the sequence of the protein-coding MAP1LC3B gene but does not encode a functional protein product[2]. Pseudogenes in general may be used as RNA transcripts with regulatory potential, including acting as decoys for microRNAs or affecting the regulation of their parent genes, but there is no established druggability, biological function, or interaction information for this specific pseudogene. The functional MAP1LC3B protein, by contrast, plays important roles in autophagy and neurogenesis, and is implicated in disease states such as cancer and metabolic disorders, but GS1-279B7.1 does not share these functions[1][2]. GS1-279B7.1 is not a protein or drug target, but a pseudogene; there is no evidence for therapeutic relevance, known function, or druggability for this entity[2][4]. For therapeutic or biological activity relevant to autophagy and microtubule function, the protein-coding MAP1LC3B gene (not the pseudogene) is the relevant entity[1][3].

Other names

GS1-279B7.1Microtubule associated protein 1 light chain 3 beta pseudogene

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