Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Microtubule Protein Tubulin Beta Chain (TUBB)
- Target
- TUBB
- Molecular classification
- Structural protein, Cytoskeletal protein
01
Overview
The tubulin beta chain is a highly conserved protein that forms heterodimers with alpha-tubulin, which are the building blocks of microtubules. Microtubules are dynamic cylindrical polymers essential for various cellular processes including structural support, intracellular transport, and cell division. The beta-tubulin subunit plays a critical role in microtubule dynamics and is a target for anti-cancer drugs that disrupt mitosis. Overexpression or mutation of specific tubulin isoforms has been linked to cancer progression, drug resistance, neurodevelopmental disorders, and other diseases.
- Other names
- Tubulin beta chainbeta-tubulin
02
Mechanism of action
Inhibition of microtubule dynamics leading to mitotic arrest.
03
Biological functions
Structural supportIntracellular transportCell divisionMicrotubule dynamics
04
Disease associations
CancerNeurodevelopmental disordersNeurodegenerationDrug resistance
05
Safety considerations
Drug resistanceNeurotoxicity
06
Interacting drugs
Taxanes
07
Biomarkers
TUBB3 expression level
Beyond the preview
Go deeper on Microtubule Protein Tubulin Beta Chain (TUBB).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Microtubule Protein Tubulin Beta Chain (TUBB).