Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Mid1-interacting protein 1 (MID1IP1)
- Target
- MID1IP1
- Molecular classification
- Other (lipogenesis regulator, not a classical drug target family)
01
Overview
Mid1-interacting protein 1 (MID1IP1) is a protein involved in the regulation of lipogenesis, notably by up-regulating the enzyme acetyl-CoA carboxylase (ACACA) activity and thus promoting the biosynthesis of fatty acids and complex lipids, mostly in the liver. It is also implicated in the regulation of microtubule stabilization. MID1IP1 is localized mainly in the cytosol, particularly associated with the microtubule cytoskeleton. Although it has been linked to some metabolic pathways and is associated with chromosome 1p36 deletion syndrome, it is not known to be a current direct therapeutic target and no specific drugs are approved that modulate its function.
- Other names
- MIG12S14RSpot 14-RSTRAIT11499FLJ10386THRSPLG12-likeGastrulation-specific G12-like proteinMid1-interacting G12-like proteinProtein STRAIT11499Spot 14-related proteinGastrulation specific G12 homolog (zebrafish)Mid1 interacting G12-like proteinMID1 interacting protein 1 (gastrulation specific G12-like)Gastrulation specific G12 homolog
02
Mechanism of action
Not applicable (no drugs known; endogenous role is up-regulation of ACACA enzyme activity, promoting lipid biosynthesis)
03
Biological functions
Regulation of lipogenesis (fatty acid and lipid biosynthesis)Positive regulation of fatty acid biosynthetic processPositive regulation of ligase activityProtein bindingMicrotubule stabilization
04
Disease associations
Chromosome 1p36 deletion syndromeOther (current evidence does not support strong direct involvement in other diseases)
05
Safety considerations
None known (no drugs target MID1IP1 and no reported safety concerns with targeting this protein)
06
Interacting drugs
None known
07
Biomarkers
None established
Beyond the preview
Go deeper on Mid1-interacting protein 1 (MID1IP1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Mid1-interacting protein 1 (MID1IP1).