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Mineral matrix in dentin

Molecular classification
Other
01

Overview

The **mineral matrix in dentin** refers to the inorganic, mineralized component of dentin, a hard tissue in teeth found beneath the enamel and surrounding the dental pulp. This matrix is composed primarily of **hydroxyapatite** crystals (calcium phosphate), which account for approximately 68–70% of dentin by weight, providing hardness and rigidity[1][3][4][5]. The mineral phase is deposited within a framework of collagen type I and smaller amounts of other proteins, which together form the organic matrix[1][3][5][8]. The precise organization and mineralization of the matrix are critical for tooth function and resilience. While essential for dentistry and dental research (such as in biomaterials or regenerative studies), **the mineral matrix in dentin is not a drug target, receptor, or defined molecular species**—it is a composite structural feature[1][3][4][5]. **Note:** This entry is marked as *is_incorrect: true*, because "Mineral matrix in dentin" is not a molecular target, protein, or classic therapeutic entity, but a descriptive term for a part of tissue composition. It cannot be targeted by drugs or mapped to classic molecular/structural target categories.

Other names
Dentin mineral phaseDentin mineralizationDentin inorganic matrix
02

Biological functions

Tooth structure and supportMineral storageMechanical protection of dental pulp
03

Disease associations

Tooth development defects (e.g., dentinogenesis imperfecta)Dental caries (via demineralization)Other dental diseases involving mineralization defects

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