Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
MIR124-2 host gene (MIR124-2HG)
- Target
- MIR124-2HG
- Molecular classification
- Long non-coding RNA (lncRNA), Non-coding RNA gene, MicroRNA host gene
01
Overview
The **MIR124-2 host gene** (MIR124-2HG) is a human long non-coding RNA (lncRNA) gene located on chromosome 8 and also known as LINC00966. It functions primarily as a non-protein coding RNA and serves as a host gene for the microRNA miR-124-2. MIR124-2HG is involved in regulating gene expression through mechanisms such as influencing mRNA translation, modulating signaling pathways, and controlling processes critical for neural development and cellular differentiation. It is also implicated in immune regulation and has emerging associations with diseases such as neurodegenerative diseases and certain cancers, likely through its regulatory influence on its embedded microRNA and related pathways[1][3][2][5]. This gene is not a conventional therapeutic target like a receptor or enzyme, and there are no known drugs that specifically interact with MIR124-2HG as a target. There are currently no established biomarkers or specific safety concerns directly related to manipulation of MIR124-2HG.
- Other names
- LINC00966long intergenic non-protein coding RNA 966MIR124-2HGMIR124-2 host gene (non-protein coding)
02
Biological functions
Regulation of gene expressionCellular signaling pathway modulationNeural development and differentiationImmune response regulation
03
Disease associations
Neurodegenerative disease (associated with Amyotrophic Lateral Sclerosis 16, Juvenile)Cancer, including suppression of epithelial-mesenchymal transition and potentially impacting apoptosis
Beyond the preview
Go deeper on MIR124-2 host gene (MIR124-2HG).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on MIR124-2 host gene (MIR124-2HG).