Target intelligence / Profile preview

MIR1302-9 host gene (MIR1302-9HG)

Target
MIR1302-9HG
Molecular classification
Other (specifically: long non-coding RNA host gene), MicroRNA host gene
01

Overview

MIR1302-9 host gene (MIR1302-9HG) is a long non-coding RNA (lncRNA) gene in the human genome that serves as the host transcript for the microRNA miR-1302-9, part of the placental-specific miR-1302 family[2][5]. The gene does not encode a protein but produces a precursor RNA transcript from which the mature microRNA miR-1302-9 is processed. miR-1302-9, like other miRNAs, modulates post-transcriptional regulation by binding to the 3' untranslated regions of target messenger RNAs, affecting processes related to cellular transportation, localization, system development, and binding/transcriptional regulation[1][5]. The MIR1302-9 host gene itself is not currently recognized as an independent therapeutic target, receptor, or enzyme, but is a genomic locus with regulatory significance as a microRNA host[1][2][5].

Other names
MIR1302-9 Host GenemiR-1302-9 host geneMIR1302-9hsa-mir-1302-9
02

Biological functions

Regulation of gene expression (by hosting intronic miRNAs)Post-transcriptional gene silencing (as miRNA precursor transcript)Possibly involved in placental development and cellular regulation (related to miR-1302 family maturation)[1]
03

Disease associations

Other (no direct evidence for a specific disease role of the host gene itself, but miR-1302 family implicated in diverse cellular pathways)[1]

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