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Mitochondrial coiled-coil domain protein 1 (MCCD1)

Target: MCCD1
Molecular classification: Other (coiled-coil domain mitochondrial protein)

Overview

Mitochondrial coiled-coil domain protein 1 (MCCD1) is a nuclear-encoded mitochondrial protein characterized by a coiled-coil domain and is located at the telomeric end of the major histocompatibility complex (MHC) class III region in humans[3][6][9]. MCCD1 is widely expressed in various tissues and is primarily localized within mitochondria[5][6][8]. Its precise physiological function remains unclear; however, related members in the coiled-coil-helix-coiled-coil-helix (CHCH) domain family are known to contribute to the structural integrity and stabilization of mitochondrial protein complexes[7]. There are no known roles for MCCD1 as a drug target, nor are there any known diseases directly associated with its mutation or dysregulation.

Other names: Mitochondrial coiled-coil domain 1Mitochondrial coiled-coil domain protein 1MCCD1

Mechanism of action

Not applicable

Biological functions

Likely involved in mitochondrial structure or functionSpecific functions are not fully elucidated, but its localization to mitochondria suggests a structural or assembly role[3][5][6][9].

Disease associations

OtherThere is no direct evidence implicating MCCD1 in major human diseases such as cancer, inflammation, neurodegenerative diseases, or cardiovascular disorders[3][6][7].

Safety considerations

None reported

Interacting drugs

None known

Biomarkers

None described

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