Mitochondrial Function in Plasmodium falciparum (N/A)

Mitochondrial function in *Plasmodium falciparum* refers to the collection of metabolic processes and structural features of the parasite's mitochondrion, which is a single, dynamic organelle essential for parasite survival, particularly via its role in pyrimidine biosynthesis. While blood-stage parasites primarily rely on glycolysis, the mitochondrial electron transport chain and other pathways are crucial for providing essential metabolites and maintaining overall viability. The unique aspects of the *P. falciparum* mitochondrion, such as its limited oxidative phosphorylation capacity and distinct ETC components, make it a target for antimalarial drug development.

Other names

Plasmodium falciparum MitochondrionPf Mitochondrion

Disruption of pyrimidine biosynthesis and/or ATP production through targeting mitochondrial electron transport chain components.