Mitochondrial ribosomal protein L3 pseudogene 1 (MRPL3P1)

Mitochondrial ribosomal protein L3 pseudogene 1 (MRPL3P1) is a processed pseudogene in the human genome that shows homology to the functional MRPL3 gene, which codes for a protein involved in mitochondrial protein synthesis as part of the mitoribosome[6]. Pseudogenes like MRPL3P1 typically do not encode functional proteins, and no evidence is available to suggest this pseudogene is transcribed or has any direct biological or disease-modifying role. The presence of MRPL3P1 does not constitute a therapeutic target, a receptor, or a functionally active molecule for pharmacological intervention[6][4]. In general, some pseudogenes may act as regulatory RNAs via microRNA decoy functions, but this is not specifically established for MRPL3P1[2]. There is nothing to suggest that MRPL3P1 is a misspelled gene symbol or incorrect in nomenclature, but it does not represent a bona fide druggable or functional target.

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