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Target intelligence / Profile preview
Mitochondrial ribosomal protein L34 (MRPL34)
- Target
- MRPL34
- Molecular classification
- Ribosomal protein, Structural protein, Mitochondrial ribosome subunit, Other
01
Overview
Mitochondrial ribosomal protein L34 (MRPL34) is a structural component of the 39S large subunit of the mitochondrial ribosome. It is encoded by a nuclear gene and imported into mitochondria, where it participates in mitochondrial protein synthesis. MRPL34 belongs to the large ribosomal subunit protein bL34 family. It has been implicated in human diseases such as combined oxidative phosphorylation deficiency 9 and Bardet-Biedl syndrome. Its primary function is as a structural constituent of the ribosome, essential for mitochondrial translation and energy production.
- Other names
- Large ribosomal subunit protein bL34mL34mtMRP-L34MGC2633MGC24974bL34m39S ribosomal protein L34, mitochondrialmitochondrial large ribosomal subunit protein bL34m
02
Biological functions
Mitochondrial protein synthesisStructural constituent of the ribosomeTranslationOther
03
Disease associations
Mitochondrial disorders (e.g., Combined oxidative phosphorylation deficiency 9)Bardet-Biedl syndromeOther
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