Mitochondrial ribosomal protein S21 pseudogene 3 (MRPS21P3)

MRPS21P3 (mitochondrial ribosomal protein S21 pseudogene 3) is a processed pseudogene in the human genome. It shares high sequence identity with the functional mitochondrial ribosomal protein S21 gene (MRPS21), but does not encode a protein product and is generally considered non-functional[2][4][3]. Processed pseudogenes, such as MRPS21P3, typically originate from reverse-transcribed mRNA sequences that have been inserted into the genome, often lacking regulatory elements required for transcription and translation[2]. While the functional MRPS21 gene encodes a protein that is part of the mitochondrial ribosome 28S small subunit, MRPS21P3 does not contribute to any ribosomal function or to mitochondrial protein synthesis[5][2]. Pseudogenes like MRPS21P3 may persist as genomic markers of evolutionary events but are not expressed as proteins and have no established role in cell biology or disease[2][3][4]. Note: If you intended to query about the functional mitochondrial ribosomal protein S21 (MRPS21), that is a bona fide protein component of the mitochondrial ribosome, but MRPS21P3 is specifically a pseudogene and not a target for drugs, diagnostics, or research applications focused on active molecular function[2][4][3][5].

Other names

MRPS21P3mitochondrial ribosomal protein S21 pseudogene 3