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Mitochondrial ribosomal protein S23 pseudogene

Molecular classification
Pseudogene, Processed pseudogene
01

Overview

The mitochondrial ribosomal protein S23 pseudogene is a genomic DNA sequence sharing high similarity with the coding MRPS23 gene, but does not encode a functional mitochondrial ribosomal protein. Pseudogenes like this are considered non-functional gene remnants and are not typically transcribed or translated into active proteins. Functional MRPS23 is a protein-coding gene critical for mitochondrial protein synthesis and has roles in cancer and mitochondrial disease, but the pseudogene itself is not biologically active and does not have a characterized role in health or disease. Important context: There are multiple pseudogenes for ribosomal protein S23 in the human genome, including ones on different chromosomes, all classified as non-functional. Occasionally, pseudogenes may be transcribed and have regulatory roles, but there is no evidence for a disease or drug-target role for the MRPS23 pseudogenes cited here. If you are looking for information on the functional gene/protein, search for "mitochondrial ribosomal protein S23" (MRPS23), not the pseudogene.

Other names
MRPS23Pmitochondrial ribosomal protein S23 pseudogene
02

Mechanism of action

Not applicable

03

Biological functions

None established for the pseudogene itself.
04

Disease associations

None attributed to the pseudogene.

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