Mitochondrial ribosomal protein S33 pseudogene 3 (MRPS33P3)

Mitochondrial ribosomal protein S33 pseudogene 3 (MRPS33P3) is classified as a processed pseudogene in the human genome. Pseudogenes are DNA sequences similar to known genes but typically non-functional due to mutations, truncations, or lack of regulatory elements; they do not produce functional proteins[4][5]. MRPS33P3 has high sequence similarity to the functional MRPS33 gene (which encodes a mitochondrial ribosomal protein important for mitochondrial protein synthesis), but MRPS33P3 itself is not known to express protein or act as a therapeutic target[2][4][5]. There is no evidence that MRPS33P3 acts as a regulatory non-coding RNA, and there are no known clinical, pathological, or pharmacological associations. This target is not considered relevant for drug discovery, biomarker development, or disease modeling[2][4][5][10]. Note: Pseudogenes can sometimes act as competitive endogenous RNAs or microRNA decoys, influencing the expression of related functional genes, but this is not reported for MRPS33P3 specifically[6]. It is important to distinguish between the functional gene (MRPS33) and this pseudogene (MRPS33P3)[1][2][5]. Summary: MRPS33P3 is a pseudogene with no known protein product, function, disease link, or drug interactions; it should not be considered a druggable target. Entries listing it as a target or protein-coding gene are incorrect.

Other names

MRPS33P3