Mitochondrial ribosomal protein S36 pseudogene 5 (MRPS36P5)

Mitochondrial ribosomal protein S36 pseudogene 5 (MRPS36P5) is classified as a *processed pseudogene*, meaning it is a DNA sequence similar to a functional gene (in this case, one encoding a mitochondrial ribosomal protein from the S36 family), but it does not produce a functional protein due to disruptive mutations or lack of regulatory elements[2][3][6]. This locus is listed in gene and protein databases (e.g., HGNC ID: 29775, NCBI Gene ID: 347703, Ensembl: ENSG00000257927)[2][3][6]. While pseudogenes as a class can sometimes exert regulatory effects at the RNA level (such as acting as microRNA decoys or sources of small interfering RNAs[4]), there is no evidence from available sources that MRPS36P5 has any such regulatory function or clinical relevance. It does not encode a protein, nor is it a receptor, enzyme, transporter, or typical drug target[3][4][6]. Pseudogenes of the mitochondrial ribosomal protein family generally originate from retrotransposition events and do not participate in cellular translation or mitochondrial biogenesis, distinguishing them from their functional counterparts, the **mitochondrial ribosomal proteins (MRPs)**, which are key components of mitochondrial ribosomes critical for oxidative phosphorylation and mitochondrial gene expression[5][7]. Unlike functional MRPs, MRPS36P5 has no recognized molecular or disease roles and carries no associated interacting drugs or known biomarker status. In summary, **MRPS36P5** is a gene fragment classified as a pseudogene related to mitochondrial ribosomal proteins, with no protein product, no established biological role, and no relevance as a therapeutic target.

Other names

MRPS36P5