Target intelligence / Profile preview

Mitochondrial transcription rescue factor 1 pseudogene 1 (MTRES1P1)

Target
MTRES1P1
Molecular classification
Other (specifically: processed pseudogene)
01

Overview

MTRES1 pseudogene 1 (MTRES1P1) is a human processed pseudogene corresponding to the mitochondrial transcription rescue factor 1 (MTRES1), annotated by HGNC as a pseudogene without coding potential for a functional protein. Unlike its parental gene MTRES1, which is a mitochondrial RNA-binding protein involved in mitochondrial transcription rescue and quality control of stalled mitoribosomes, the pseudogene MTRES1P1 does not encode any known protein or have assigned functional or disease associations. Although pseudogenes in general may exert effects through regulatory RNA mechanisms or serve as disease biomarkers, there is currently no evidence for MTRES1P1 participating in such functions. It is cataloged for genomic reference and does not serve as a therapeutic or clinical target.

Other names
MTRES1 pseudogene 1MTRES1P1mitochondrial transcription rescue factor 1 pseudogeneHGNC:54502
02

Mechanism of action

No mechanisms described for any drugs targeting this pseudogene.

03

Biological functions

As a pseudogene, it has no confirmed protein or biological functionPseudogenes can participate in regulatory RNA functions (e.g. competing for miRNAs, influencing parental gene expression), but there is no evidence for MTRES1P1 in such roles
04

Disease associations

None specifically known for MTRES1P1By analogy to other pseudogenes, pseudogenes as a class can be biomarkers and play a role in cancer or disease progression, but no evidence links MTRES1P1 to such roles

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