Mitochondrially encoded ATP synthase 6 pseudogene 3 (MTATP6P3)

Mitochondrially encoded ATP synthase 6 pseudogene 3 (MTATP6P3) is a nuclear-encoded pseudogene homologous to the mitochondrial gene MT-ATP6, which encodes a vital subunit of mitochondrial ATP synthase responsible for ATP production[1][2][7]. As a pseudogene, MTATP6P3 does not encode a functional protein and has no known biological, disease, or pharmacological roles. It should not be mistaken for the functional MT-ATP6 gene, whose mutations are associated with mitochondrial disorders such as Leigh syndrome and NARP syndrome[1][2][4][5]. Pseudogenes like MTATP6P3 may arise from duplication or transfer events but do not produce active gene products or serve as drug targets. If seeking information on therapeutic targets, the correct molecule is the functional MT-ATP6 gene, not MTATP6P3.

Other names

MT-ATP6 pseudogene 3MTATP6P3mitochondrially encoded ATP synthase 6 pseudogene 3