Target intelligence / Profile preview

Mitochondrially encoded cytochrome c oxidase I pseudogene 18 (MTCO1P18)

Target
MTCO1P18
Molecular classification
Other (Pseudogene)[3]
01

Overview

MTCO1P18 (Mitochondrially encoded cytochrome c oxidase I pseudogene 18) is classified as a pseudogene, meaning it is a segment of DNA that resembles a gene but is non-functional; that is, it does not code for a functional protein or enzyme in the cell. Its sequence is similar to that of the functional mitochondrial gene MT-CO1, which encodes a subunit of the cytochrome c oxidase complex involved in mitochondrial electron transport, but MTCO1P18 itself does not have a recognized biological function or disease association[3]. There is no evidence in public databases or biomedical literature to suggest MTCO1P18 acts as a therapeutic target, is involved in disease biology, or interacts with drugs. It is listed in genomic databases for completeness but does not have a known role in physiology or pathology. Key points: - MTCO1P18 is a pseudogene copy of MT-CO1 located in the nuclear genome, not the mitochondrial genome. - It is not considered a drug target due to lack of protein product or biological function. - There are no established disease roles, molecular interactions, or safety concerns associated with MTCO1P18[3]. - This entry is not misspelled or otherwise problematic, but it should not be confused with the functional mitochondrial gene MT-CO1, which *is* disease-relevant but is a separate entity[1][3].

Other names
MT-CO1 Pseudogene 18MTCO1P18[3]

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