Mitochondrially encoded cytochrome c oxidase III pseudogene 20 (MTCO3P20)

MT-CO3 pseudogene 20 (MTCO3P20) is a human pseudogene related to the functional mitochondrial gene *MT-CO3*, which encodes cytochrome c oxidase subunit III, a component of the electron transport chain[1][2][4]. As a pseudogene, MTCO3P20 contains sequence homology to MT-CO3 but lacks protein-coding and functional biological activity. It is formally annotated in gene databases (e.g., GeneCards, NCBI) as a pseudogene and shares its name with the protein-coding MT-CO3 gene but does not produce a functional protein. There is no evidence that MTCO3P20 acts as a therapeutic target, plays a direct biological role, or is associated with disease or drug interactions[2][4]. Key clarifications: - MTCO3P20 is biologically distinct from the functional MT-CO3 gene, which encodes cytochrome c oxidase subunit III[1][3][8]. - Pseudogenes are considered nonfunctional genetic elements; therefore, they are not receptor, enzyme, transporter, or otherwise considered druggable or therapeutic targets[2][4]. - There is no indication of errors in the reference to MTCO3P20; it is annotated and listed in established databases[2][4].

Other names

MT-CO3 pseudogene 20mitochondrially encoded cytochrome c oxidase subunit 3 pseudogene 20MTCO3P20