Mitochondrially encoded NADH dehydrogenase 3 pseudogene

The mitochondrially encoded NADH dehydrogenase 3 pseudogene (ENSG00000283176) is a non-functional segment of DNA that resembles the MT-ND3 gene, which normally codes for a subunit of Complex I (NADH:ubiquinone oxidoreductase) in the mitochondrial electron transport chain. As a pseudogene, it does not code for a functional protein and does not have a role in oxidative phosphorylation or disease. Pseudogenes may arise from gene duplication or retrotransposition events and are generally considered genetic relics without functional relevance in metabolism or disease mechanisms[1][2]. Key clarifications: - MT-ND3 is a functional mitochondrial gene, but this entry refers specifically to a pseudogene, which lacks function[1]. - Pseudogenes are not considered drug targets because they do not produce active proteins. - There is no evidence from GeneCards, NCBI, or related databases that this pseudogene has regulatory, biomarker, or clinical relevance. Summary judgment: This entry is not a therapeutic or functional target and appears in error for most target-focused applications. If you're searching for the protein-coding gene, refer to MT-ND3 (NADH dehydrogenase subunit 3), not its pseudogene[1][12].

Other names

MT-ND3 pseudogeneMTND3PNADH dehydrogenase subunit 3 pseudogene