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Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 pseudogene 41 (MTND2P41)

Target
MTND2P41
Molecular classification
Other (Pseudogene)
01

Overview

MTND2P41 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 pseudogene 41) is a nuclear-encoded human pseudogene located at chromosome 4q13.2. It is a non-functional segment of DNA that resembles the protein-coding mitochondrial gene MT-ND2 but does not encode a functional protein and has not been shown to produce a transcript with biological activity. MTND2P41 has no established role in normal cellular biology, disease, or drug response, and is not considered a target for pharmacological intervention. This differs from the functional mitochondrial gene MT-ND2, which encodes a subunit of Complex I involved in the mitochondrial electron transport chain.

Other names
MT-ND2 pseudogene 41MTND2P41mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 pseudogene 41
02

Biological functions

Other (No known protein-coding or catalytic function. Some evidence suggests potential transcriptional roles of pseudogenes in gene regulation, but none reported specifically for MTND2P41.)
03

Disease associations

Other (No direct disease associations or roles reported. The functional gene MT-ND2 is implicated in neurodegenerative and metabolic diseases, but no evidence exists for the pseudogene MTND2P41.)

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