Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L pseudogene 23 (MTND4LP23)

This locus (ENSG00000259600) represents a pseudogene related to the functional mitochondrial gene MT-ND4L, which encodes a protein subunit of mitochondrial respiratory Complex I. Pseudogenes do not produce functional proteins and are typically non-coding remnants of ancestral genes. There is no evidence for this locus being a receptor, enzyme, transporter, or any functional therapeutic target. Its presence is mainly of genomic and evolutionary interest, without direct biological function, disease association, or drug targeting relevance in current biomedical research[6]. Clarifying notes: - The confusion may arise because the canonical MT-ND4L gene is a mitochondrial genome-encoded subunit of Complex I that is clinically relevant (e.g., associated with Leber hereditary optic neuropathy), but ENSG00000259600 and the provided aliases refer to a nuclear-encoded pseudogene homolog of MT-ND4L, which is not a functional target[1][2][6]. - This target should not be used in the context of drug discovery or therapeutic research, as it does not encode a functional protein and lacks established roles in human biology or disease[6].

Other names

MTND4P38MT-ND4 pseudogene 38mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 pseudogene 38mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L pseudogene 23MTND4LP23