Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 pseudogene 4 (MTND5P4)

MT-ND5 pseudogene 4 (MTND5P4) is a nuclear pseudogene related to the mitochondrial gene encoding NADH:ubiquinone oxidoreductase core subunit 5 (MT-ND5), a critical protein of mitochondrial complex I[4][2]. Unlike the functional mitochondrial gene, this pseudogene contains mutations—including premature stop codons—that prevent it from being translated into a functional protein[1]. As such, it does not play a direct role in cellular metabolism or serve as a therapeutic target like true enzymes, receptors, or transporters. Its designation in the genome reflects sequence homology but not function; pseudogenes like MTND5P4 do not produce active proteins and are generally not involved in drug action or disease mechanisms, though some nuclear pseudogenes may have regulatory functions in rare cases[1][2][4].

Other names

MT-ND5 pseudogene 4MTND5P4