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Mitogen-activated protein kinase kinase 1 pseudogene 1 (MAP2K1P1) is a non-functional genomic sequence resembling the MAP2K1 gene, which encodes a dual-specificity protein kinase involved in signal transduction. MAP2K1P1 is not translated into a functional protein and does not serve as an enzyme, receptor, or druggable target in human biology. Its presence is primarily of interest for genomic annotation and has no established role in cellular function, disease, or therapeutic intervention. Note: This target is sometimes listed in genomic databases due to its sequence similarity to the functional MAP2K1 gene, but it should not be confused with MAP2K1 (MEK1), which is a bona fide therapeutic target in oncology and other fields.
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