Mitosis Pathway

The mitosis pathway is the process by which a eukaryotic cell divides its nucleus and genetic material, resulting in two genetically identical daughter cells. This pathway is essential for growth, tissue repair, and asexual reproduction in multicellular organisms. It involves a series of distinct phases (prophase, prometaphase, metaphase, anaphase, telophase, and cytokinesis) that ensure precise segregation of chromosomes. Regulation is achieved through checkpoints, CDKs, and other signaling pathways. Dysregulation of this pathway is a hallmark of cancer, and many anti-cancer drugs target specific proteins involved in mitosis.

Other names

Cell Division PathwayM PhaseNuclear DivisionChromosome Segregation

Various, depending on the specific drug. Examples include: Microtubule stabilization (taxanes), microtubule destabilization (vinca alkaloids), inhibition of kinases involved in cell cycle progression (CDK inhibitors, Aurora kinase inhibitors).