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Target intelligence / Profile preview
Mitotic spindle organizing protein 2B (MZT2B)
- Target
- MZT2B
- Molecular classification
- Other (protein component of the gamma-tubulin ring complex; does not fit common drug target classes like receptor, ion channel, or enzyme)
01
Overview
Mitotic spindle organizing protein 2B (MZT2B) is a protein-coding gene that encodes a component of the gamma-tubulin ring complex (gTuRC), a multiprotein structure essential for the nucleation and organization of microtubules at the centrosome and mitotic spindle. It is required for the recruitment and assembly of the gamma-tubulin ring complex at the centrosome, supporting the formation of the mitotic spindle during cell division. There is no evidence in curated biomedical databases that MZT2B is currently a therapeutic target or is directly linked to specific diseases or interacting drug compounds[3][5][7][8].
- Other names
- FAM128BMOZART2BFLJ14346mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2Bmitotic spindle organizing protein 2B
02
Biological functions
Microtubule organizationCentrosome functionCell divisionSpindle assembly
03
Disease associations
Other (no well-established disease roles such as cancer or inflammation have been documented in curated sources)
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