Mitotic spindle organizing protein 2B pseudogene (MZT2B pseudogene)

The “mitotic spindle organizing protein 2B pseudogene” (ENSG00000278337) is a genomic sequence categorized as a pseudogene. Unlike the functional MZT2B gene, which encodes a protein required for the assembly of the gamma-tubulin ring complex at the centrosome and contributes to mitotic spindle formation, the pseudogene is generally non-coding and does not produce a functional protein. Pseudogenes originate from protein-coding genes but acquire disabling mutations preventing protein expression, and their biological significance is usually limited unless specifically shown to have regulatory RNA function. No therapeutic drug targets, disease associations, or biological functions have been documented for this pseudogene.

Other names

MZT1P2Mitotic spindle organizing protein 1 pseudogene 2

None relevant; no known mechanism for therapeutic modulation applies to pseudogenes