MOB kinase activator 1A pseudogene 1 (MOB1AP1)

MOB kinase activator 1A pseudogene 1 (MOB1AP1) is a human pseudogene related to the family of Mps One Binder (MOB) coactivator proteins, particularly the MOB1A protein, which is involved in the Hippo signaling pathway, cell proliferation, and regulation of organ size [1][4]. Unlike the functional MOB1A gene, MOB1AP1 does not encode an active protein and does not have a characterized biological or disease role. It is not considered a drug target and should not be confused with MOB1A, which is implicated in tumor progression and may serve as a potential biomarker or therapeutic target in ovarian and other cancers [5]. The existence of pseudogenes like MOB1AP1 may reflect evolutionary duplication and divergence, but their biological relevance is minimal compared to the functional gene. Key Points: - MOB1AP1 is a pseudogene, not a functional protein or therapeutic target [1]. - Functional data and disease relevance belong to MOB1A, the active kinase coactivator involved in Hippo signaling and cancer [5]. - No drugs or biomarkers are associated with MOB1AP1; research focuses on MOB1A for therapeutic relevance and prognosis [5]. - For structured biological/therapeutic data, refer to MOB kinase activator 1A (MOB1A), not MOB1AP1.

Other names

MOBKL1BP1MOB1 Mps One Binder homolog A pseudogene 1MOB1, Mps One Binder kinase activator-like 1B pseudogene 1