Target intelligence / Profile preview

MOB kinase activator 3A (MOB3A)

Target
MOB3A
Molecular classification
Enzyme regulator (protein kinase activator), Adapter protein, Other (member of MOB kinase activator family)
01

Overview

**MOB kinase activator 3A** is a protein-coding gene that encodes a protein believed to serve as a regulator of kinases, most notably functioning as a protein kinase activator[1][5][7]. It is involved in signal transduction and is predicted to operate in both the cytoplasm and nucleus[1][4][6][7]. The gene is a member of the MOB kinase activator family, sharing similarity with other MOB proteins, and its biological role involves acting upstream in phosphorylation pathways[1][2][4]. Diseases associated with mutations or dysregulation of MOB3A include lung occult small cell carcinoma, with further research needed to clarify broader clinical relevance[1]. No approved drugs or established clinical biomarkers specifically target MOB3A, and it is not considered a canonical therapeutic target at this time, though it remains of research interest for its role in kinase regulation.

Other names
MOBKL2AMOB3A_HUMANMOB kinase-like protein 2A[1][2][7]
02

Biological functions

Protein kinase activator activitySignal transductionRegulation of phosphorylation
03

Disease associations

Cancer (notably associated with lung occult small cell carcinoma)Other (emerging roles under investigation; limited direct disease linkage evidence)

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