Molybdenum cofactor synthesis 3 pseudogene (MOCS3P)

The molybdenum cofactor synthesis 3 pseudogene (ENSG00000276569) is a **nonfunctional DNA sequence highly homologous to the functional MOCS3 gene**, which encodes adenylyltransferase and sulfurtransferase required for molybdenum cofactor biosynthesis[1][3][8]. Pseudogenes like this one generally do not encode functional protein products due to mutations such as frameshifts or premature stop codons, and are not considered part of conventional molecular target classes[1][3]. Though the parent gene MOCS3 is central to molybdenum cofactor biosynthesis and can be associated with metabolic pathways or rare genetic diseases, pseudogenes themselves are typically not drug targets nor direct participants in disease etiology[2][6][8]. However, some pseudogenes have been found to exhibit regulatory roles at the RNA level, potentially affecting gene expression, but there is currently no evidence that this pseudogene exerts such effects[5][7]. It is important in genome annotation and molecular studies to distinguish such pseudogenes from their functional counterparts to avoid amplification bias and misinterpretation[3]. **Note:** This entry is frequently **misannotated or misunderstood as a functional gene or target**; care must be taken to distinguish the pseudogene record from the functional *MOCS3* gene[1][3][4][8].

Other names

MOCS3Pmolybdenum cofactor synthesis 3 pseudogene 2MOCS3P1