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MON2 antisense RNA 1 (MON2-AS1), also known as AC079035.1, is a long non-coding antisense RNA found on chromosome 12 in humans[1]. Antisense RNAs are single-stranded RNAs transcribed from the DNA strand opposite to protein-coding genes, and their primary function is regulating gene expression of sense transcripts[3][5]. While some antisense RNAs (asRNAs) have known roles in gene silencing, chromatin remodeling, or epigenetic regulation, there is currently no direct evidence that MON2-AS1 functions as a therapeutic target, disease biomarker, or interacts with approved drugs[1][3][5]. Its classification as a therapeutic target is not supported by available data; it is best considered a regulatory non-coding RNA with possible, but not specifically elucidated, roles in gene expression regulation.
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