Target intelligence / Profile preview

Monkeypox Virus (MPXV)

Target
MPXV
Molecular classification
Virus, Orthopoxvirus, dsDNA Virus
01

Overview

The monkeypox virus (MPXV), also known as the mpox virus, is an enveloped double-stranded DNA virus belonging to the genus *Orthopoxvirus* in the family *Poxviridae*. It is a zoonotic virus that can transmit from animals to humans and between humans via close contact, respiratory droplets, or contaminated materials. MPXV causes monkeypox, an infectious disease characterized by fever, malaise, lymphadenopathy, and a distinctive rash that progresses through various stages. There is no specific antiviral treatment approved solely for mpox infection.

Other names
Mpox VirusMPXV
02

Mechanism of action

N/A

03

Biological functions

Viral ReplicationImmune EvasionInfectionZoonotic Transmission
04

Disease associations

InfectionMonkeypox (Mpox)
05

Safety considerations

Potential for severe illness, especially in immunocompromised individuals, pregnant women, and childrenRisk of complications during infection
06

Interacting drugs

Smallpox vaccines (cross-protection)

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