Target intelligence / Profile preview

Monkeypox Virus Antigen A35 Protein (A35R)

Target: A35R
Molecular classification: Viral Envelope Glycoprotein

Overview

The Monkeypox virus antigen A35 protein (A35R) is a viral envelope glycoprotein essential for cell-to-cell spread and virulence. It plays a crucial role in immunomodulation, increasing viral pathogenicity by suppressing host immune responses. As a surface protein, it serves as a key antigenic target for neutralizing antibodies and diagnostic assays.

Other names: MPXV-A35MPXV-A35ROrthopoxvirus envelope glycoprotein

Mechanism of action

N/A

Biological functions

Cell-to-cell spreadImmunomodulationViral virulence

Disease associations

MonkeypoxViral infection

Safety considerations

Potential for immune evasionSequence variation impacting vaccine efficacy

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