Target intelligence / Profile preview

Monkeypox Virus Antigen M1 Protein

Molecular classification
Viral protein, Surface membrane protein
01

Overview

The Monkeypox virus antigen M1 protein (M1R) is a myristoylated surface membrane protein found in the intracellular mature virion (IMV) form of the monkeypox virus. It plays a crucial role in viral particle assembly and entry into host cells and is a major target of neutralizing antibodies. It is highly conserved among orthopoxviruses.

Other names
M1RMPXV-M1RMonkeypox virus antigen M1 protein
02

Mechanism of action

Neutralization of viral entry

03

Biological functions

Viral particle assemblyViral entry into host cellsImmune response
04

Disease associations

InfectionMonkeypox

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