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Monoaminergic System
- Molecular classification
- Neurotransmitter System
01
Overview
The monoaminergic system refers to the network of neurons that utilize monoamine neurotransmitters, including serotonin, dopamine, norepinephrine, epinephrine, and histamine. This system plays crucial roles in regulating emotion, arousal, attention, memory, motor control, and autonomic functions. It is also involved in the modulation of neurotrophic factors. The monoaminergic system is a major target for drugs treating psychiatric and neurological disorders.
02
Mechanism of action
Various, including receptor agonism/antagonism, reuptake inhibition, enzyme inhibition, and modulation of neurotransmitter release.
03
Biological functions
Modulation of moodModulation of emotionModulation of arousalModulation of memoryModulation of motor controlModulation of autonomic processesNeurotrophic factor modulation
04
Disease associations
DepressionAnxiety disordersSchizophreniaParkinson’s diseaseADHDNarcolepsy
05
Interacting drugs
SSRIs
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