Mps one binder kinase activator-like 3 pseudogene (MOB1-like 3 pseudogene)

Mps one binder kinase activator-like 3 pseudogene (ENSG00000254758) is annotated as a pseudogene in the human genome, meaning it is a DNA sequence similar to a protein-coding gene but is generally considered non-functional and does not produce a functional protein. It should not be confused with the functional MOB1 genes (such as MOB1A or MOB1B), which are core components of the Hippo signaling pathway and play roles in cell cycle regulation, cell proliferation, and tumorigenesis[1][3]. Notes on confusion: - MOB1A (Mps one binder kinase activator 1A) and related MOB1 proteins are active components with established function in the Hippo pathway, involved in tumor biology and cell cycle regulation[1][3]. However, your query specifically references a pseudogene (MOB1KL3/ENSG00000254758), which is not itself an active target. - Pseudogenes do not encode active proteins and are generally not considered therapeutic targets, nor do they have known biomarker or pharmacological relevance. Summary: There is likely a confusion in the query between MOB1 family functional proteins and the MOB1-like 3 pseudogene. The latter is not a therapeutic target, has no established biological function, does not interact with drugs, and is not associated with disease processes directly. If the intention was to retrieve information for MOB1A/B, those are active Hippo pathway kinases involved in cancer and cell cycle regulation[1][3], but that is NOT what ENSG00000254758 encodes.

Other names

MOBKL3PMOB1 pseudogeneMps one binder kinase activator-like 3 pseudogene