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mRNA of Apolipoprotein B-100 (ApoB-100 mRNA)

Target: ApoB-100 mRNA
Molecular classification: mRNA, Gene Product

Overview

The mRNA of Apolipoprotein B-100 (ApoB-100) encodes a large protein essential for lipid transport and metabolism. ApoB-100, the full-length product expressed primarily in the liver, is crucial for the assembly and secretion of very low-density lipoproteins (VLDL), precursors to low-density lipoproteins (LDL). The APOB gene also produces a shorter isoform, ApoB-48, via RNA editing in the intestine.

Other names: APOB mRNAApolipoprotein B mRNAmRNA of APOB

Biological functions

Template for protein synthesisLipid transport regulation (indirectly through ApoB-100 protein)Cholesterol homeostasis (indirectly through ApoB-100 protein)

Disease associations

Cardiovascular disease (indirectly through ApoB-100 protein dysregulation)

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