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The mRNA turnover 4 homolog pseudogene is a genomic sequence that resembles the gene encoding a protein involved in mRNA turnover, but carries mutations such as stop codons, frameshifts, or deletions which prevent it from producing a functional protein[1][3][6]. Pseudogenes like this may sometimes be transcribed into RNA and can participate in regulatory networks, for example, by acting as RNA sponges for microRNAs and modulating the expression of their parental genes[6][7]. However, most pseudogenes, including this one, have limited or no proven biological function and are not considered therapeutic targets in biomedical research[1][3][6]. The designation "pseudogene" signals it is generally non-functional at the protein level and not a receptor, enzyme, transporter, or transcription factor. It is not a candidate for therapeutic intervention[1][3][6].
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