MT-CO1 pseudogene 38 (MTCO1P38)

MT-CO1 pseudogene 38 (MTCO1P38) is a genomic DNA sequence that is homologous to the functional mitochondrial gene MT-CO1, which encodes subunit I of cytochrome c oxidase, a key component of the mitochondrial respiratory chain. As a pseudogene, MTCO1P38 does not encode a functional protein and therefore lacks enzymatic or receptor activity. Pseudogenes arise during evolution through gene duplication or retrotransposition and typically accumulate mutations that render them non-functional. There is currently no evidence that MTCO1P38 has biological functions, disease relevance, or utility as a therapeutic target[3]. The *functional* MT-CO1 gene encodes a subunit of cytochrome c oxidase and is essential for mitochondrial respiration, with mutations linked to a range of human diseases[1][2]. However, MTCO1P38 is a *pseudogene* and not considered a direct therapeutic target, nor is it known to play a role in any human pathology[3]. If you are seeking information on the active enzyme or target, the term "MT-CO1" or "cytochrome c oxidase subunit I" should be used instead[1][2].

Other names

MTCO1P38