MT-CO2 pseudogene 20 (MTCO2P20)

MT-CO2 pseudogene 20 (MTCO2P20) is annotated as a human nuclear pseudogene with sequence similarity to the mitochondrial gene encoding cytochrome c oxidase subunit II (MT-CO2). As a pseudogene, it contains sequence elements related to the protein-coding gene but does not encode a functional protein and has no known biological activity. It is part of the large family of processed mitochondrial pseudogenes (NUMTs) found in the human genome. Current databases contain no evidence that MTCO2P20 is translated or involved in disease, biological function, or therapeutic targeting[5]. Key Notes and Evidence: - MTCO2P20 is present in the human genome as a pseudogene, meaning it is related by sequence to a functional gene (MT-CO2) but is not itself functional[5]. - Unlike the functional MT-CO2 gene, which encodes cytochrome c oxidase subunit II (a key enzyme in mitochondrial electron transport)[1][7], MTCO2P20 does not code for a protein and is not implicated in mitochondrial function, disease, or as a drug target[5]. - Some pseudogenes can have regulatory functions (e.g., as competitive endogenous RNAs), but there is currently no published evidence for such a function for MTCO2P20. - There is no evidence of confusion or incorrectness in the designation, spelling, or classification of MTCO2P20 as a pseudogene.

Other names

MTCO2P20MT-CO2 pseudogene 20mitochondrially encoded cytochrome c oxidase II pseudogene 20