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MT-CO2 pseudogene 22 is a human pseudogene located on chromosome 5 (chr5:100052859-100053539, hg38). It is a nonfunctional segment of DNA resembling the mitochondrial MT-CO2 gene, which encodes cytochrome c oxidase subunit II—a critical component of the electron transport chain complex IV. Unlike the functional MT-CO2 gene, MTCO2P22 does not encode a functional protein and has no direct biological or therapeutic role. Pseudogenes like MTCO2P22 typically arise from gene duplication or retrotransposition events and may serve as evolutionary substrates or have regulatory functions in rare cases, but no such activities are documented for this locus. MTCO2P22 is a correctly annotated pseudogene, not a functional protein target, enzyme, receptor, or therapeutic target. No interactions, disease associations, or clinically relevant properties are reported for this locus.
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