MT-CO3 pseudogene 17 (MTCO3P17)

MT-CO3 pseudogene 17 (MTCO3P17) is a human, non-protein-coding pseudogene related to the MT-CO3 gene, which encodes cytochrome c oxidase subunit III, a component of the mitochondrial respiratory chain. As a pseudogene, MTCO3P17 does not encode a functional protein or contribute directly to biochemical or signaling pathways. It serves no known therapeutic, enzyme, transporter, or receptor function and is not associated with known diseases, drug interactions, or biomarker roles. Its primary significance is in genomics as a member of the large family of mitochondrial pseudogenes in the nuclear genome[2][4]. MTCO3P17 is explicitly annotated as a pseudogene and not an active protein-coding gene[2][4]. The related functional gene, MT-CO3, encodes a key subunit in cytochrome c oxidase, a terminal enzyme complex in the mitochondrial electron transport chain, but this is not true for MTCO3P17[1][3][7]. MTCO3P17 has no documented protein product, biological function, therapeutic targeting, or clinical disease association[2][4]. No known drugs, mechanisms of action, or biomarker use are associated with this pseudogene[2][4]. There is nothing incorrect or misspelled about the designation; the information is accurate as given in genomic resources[4]. The main caveat is that, being a pseudogene, MTCO3P17 is not a biomedical target and shares only sequence homology with the functional mitochondrial gene MT-CO3.

Other names

mitochondrially encoded cytochrome c oxidase III pseudogene 17