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MT-CO3 pseudogene 19 (MTCO3P19) is classified as a pseudogene, meaning it is a DNA sequence similar to an active gene (here, the mitochondrial MT-CO3 gene encoding cytochrome c oxidase subunit III), but it does not produce a functional protein product in humans[6]. Pseudogenes lack biological activity and are not considered drug targets, nor are they implicated in disease, except in rare cases involving regulatory RNA roles—which are not established for MTCO3P19. Its entry in databases (e.g., GeneCards, HGNC) is for reference and genomic annotation only[6]. The actual gene *MT-CO3* encodes a functional subunit of cytochrome c oxidase (Complex IV of the mitochondrial respiratory chain), but *pseudogene* designations like MTCO3P19 do **not** result in active proteins and thus are not of therapeutic or biomarker interest[1][3][6]. There are many such pseudogenes in the human genome, often named after their parent gene but with numbering to distinguish non-functional copies.
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