MT-CYB pseudogene 12 (MTCYBP12)

MT-CYB pseudogene 12 (MTCYBP12) is a pseudogene; it is an inactive, non-coding copy related to the active MT-CYB gene, which encodes mitochondrial cytochrome b, a component of complex III (ubiquinol-cytochrome c reductase) in the mitochondrial respiratory chain. However, as a pseudogene, MTCYBP12 does not code for a functional protein and has no recognized biological function or disease association. It is mainly of interest as a genomic locus rather than a therapeutic target or biomarker. Pseudogenes are segments of DNA that resemble functional genes but are typically nonfunctional due to mutations. They do not code for active proteins and do not act as therapeutic targets. MT-CYB (the functional version) is sometimes a disease locus, but MTCYBP12 itself, being a pseudogene, has no known role in disease or drug response and is not an enzyme, receptor, or other typical molecular target. There is nothing incorrect about the name given the context, but there is a common confusion between this pseudogene (MTCYBP12) and the protein-coding mitochondrial gene (MT-CYB/CYTB), a genuine target with disease relevance.

Other names

MT-CYB pseudogene 12MTCYBP12