MT-CYB pseudogene 37 (MTCYBP37)

MT-CYB pseudogene 37 (MTCYBP37) is a human nuclear pseudogene designated on chromosome 5 (chr5:8619178-8620310, hg38). It originates as a non-functional homolog of the mitochondrial cytochrome b gene (MT-CYB), likely through historic gene transfer or duplication events. Unlike the functional MT-CYB gene, which encodes the cytochrome b protein essential for mitochondrial electron transport and ATP synthesis[1][3][5], the pseudogene sequence does not encode a functional protein and has no known physiological or pathological role. It is sometimes referenced in genome annotations but should not be confused with the true MT-CYB gene, which is a component of mitochondrial complex III and associated with oxidative phosphorylation, rare mitochondrial disorders, and other clinical phenotypes[1][5][7]. If your query intended the actual druggable mitochondrial target (MT-CYB), refer instead to "mitochondrially encoded cytochrome b (MT-CYB)," an enzyme with well-established biological and disease associations. The entry provided here, "MT-CYB pseudogene 37 (MTCYBP37)," is not a therapeutic target and has no protein product or drug interactions[2].

Other names

MT-CYB pseudogene 37MTCYBP37ENSG00000248765 (Ensembl)NCBI Gene 109729151

None applicable.