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Target intelligence / Profile preview
MT-ND1 pseudogene 18 (MTND1P18)
- Target
- MTND1P18
- Molecular classification
- Pseudogene
01
Overview
MT-ND1 pseudogene 18 (MTND1P18) is a genomic sequence homologous to the mitochondrial gene MT-ND1, but it is classified as a pseudogene because it does not encode a functional protein. Unlike the canonical MT-ND1 gene, which codes for a mitochondrial complex I subunit involved in electron transport and ATP production, MTND1P18 has no known biological function or disease association. It is listed in gene databases (e.g., NCBI Gene, HGNC) as a pseudogene, and is not considered a drug target or biochemical entity for therapeutic intervention[2][6].
- Other names
- MTND1P18MT-ND1 pseudogene 18Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 pseudogene 18
02
Mechanism of action
Not applicable (no known drugs acting on this pseudogene)
03
Biological functions
None established (pseudogenes generally have no protein-coding biological function; MTND1P18 is not known to be transcribed into a functional protein)
04
Disease associations
No direct disease roles.Some mitochondrial pseudogenes are investigated as biomarkers in tissue-specific gene expression studies, but MTND1P18 itself is not established as a disease gene, nor is it implicated in mitochondrial disease states or pathophysiology
05
Safety considerations
None described (as it is not a therapeutic target)
06
Interacting drugs
None known (as it is not a protein or biochemical target)
07
Biomarkers
None established for patient selection or monitoring
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