MT-ND1 pseudogene 33 (MTND1P33)

MT-ND1 pseudogene 33 (MTND1P33) is a non-coding pseudogene listed in gene databases such as NCBI Gene (ID: 100873218) and Ensembl (ENSG00000235539)[2][9]. It shares sequence similarity with the functional gene MT-ND1, which encodes a core subunit of the mitochondrial respiratory chain complex I, but MTND1P33 itself does not produce a functional protein or contribute to mitochondrial energy metabolism. There is currently no evidence to suggest MTND1P33 plays a direct role in biological function, pathology, or therapy. Its presence is generally considered genomically inert and is not involved in drug development, mechanism of disease, or therapeutic safety monitoring. All functional and disease relevance cited for MT-ND1 does not apply to MTND1P33, as those roles pertain only to the coding parent gene[1][7][8][9]. If you are seeking information on the active, protein-coding mitochondrial gene (MT-ND1) rather than the pseudogene (MTND1P33), more extensive information is available regarding its function in mitochondrial energy metabolism and disease roles[1][3][7][8]. Please clarify if that is the intended target.

Other names

MT-ND1 pseudogene 33MTND1P33mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 pseudogene 33