MT-ND2 pseudogene 23 (MTND2P23)

MT-ND2 pseudogene 23 (MTND2P23) is designated as a pseudogene related to the mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 (MT-ND2), which is a component of mitochondrial Complex I involved in the electron transport chain[1][3]. Pseudogenes are DNA sequences similar to normal genes but are nonfunctional; there is currently no evidence that MTND2P23 produces a functional protein or plays a biological role in cellular processes. A recent study identified differential expression of certain mitochondrial pseudogenes, including MT-ND2 pseudogenes, in the brains of Alzheimer’s disease patients, but their precise function and significance remain unclear, and no studies have shown MTND2P23 itself as a therapeutic target or implicated it in disease mechanisms[2]. As a pseudogene, it is not considered a therapeutic target, nor is it classified under established molecular families such as receptor, enzyme, transporter, or transcription factor. There is no evidence for drug interaction, clinical biomarker value, or safety concerns related to MTND2P23. Key points: MTND2P23 is a mitochondrial pseudogene, not a receptor, enzyme, or functional protein. It is not considered a therapeutic target. There is insufficient information about its biological function, disease role, or involvement in drug interactions. Pseudogenes like MTND2P23 may be differentially expressed in some disease states (such as Alzheimer’s disease), but their clinical or mechanistic relevance is unclear[2]. This target may not be correct for therapeutic or mechanistic investigation due to lack of functional evidence.

Other names

MTND2P23mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 pseudogene 23