MT-ND2 pseudogene 6 (MTND2P6)

MT-ND2 pseudogene 6 (MTND2P6) is a nuclear pseudogene of the mitochondrial gene MT-ND2, which encodes an essential subunit of the mitochondrial NADH dehydrogenase (Complex I) involved in oxidative phosphorylation[2][7]. Unlike functional protein-coding genes, pseudogenes like MTND2P6 do not translate into proteins and generally lack direct biological function. Most research, functional, and disease associations center on MT-ND2, while studies of MTND2P6 itself are rare, and it is not considered a therapeutic target, receptor, enzyme, or transporter. Reports describing mitochondrial pseudogenes note that further research is needed to clarify their potential biological impact, but currently MTND2P6 is primarily noted for genomic annotation rather than clinical or experimental relevance[2][7]. This entry should not be used as a canonical therapeutic target due to its status as a pseudogene and lack of biological activity[2][7].

Other names

MTND2P6mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 pseudogene 6