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Target intelligence / Profile preview
MT-ND3 pseudogene 13 (MTND3P13)
- Target
- MTND3P13
- Molecular classification
- Other (Pseudogene)
01
Overview
MT-ND3 pseudogene 13 is a pseudogene located on human chromosome 16 (chr16:10723424-10723766, hg38 coordinate), named for its sequence similarity to the functional MT-ND3 gene found in mitochondrial DNA. MTND3P13 does not encode a functional protein and has no reported biological activity or clinical relevance. By contrast, its mitochondrial counterpart (MT-ND3) is a core subunit of mitochondrial respiratory chain complex I, and pathogenic variants in MT-ND3 contribute to mitochondrial diseases such as Leigh syndrome, MELAS, and optic neuropathy. However, these disease and drug associations do not apply to the pseudogene MTND3P13.
- Other names
- MTND3P13MT-ND3 Pseudogene 13
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