MT-ND3 pseudogene 22 (MTND3P22)

MT-ND3 pseudogene 22 (MTND3P22) is a nuclear-encoded pseudogene related to the mitochondrial gene MT-ND3, which codes for a component of mitochondrial complex I[2]. It is also known as mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 pseudogene 22. As a pseudogene, MTND3P22 does not produce a functional protein and does not participate in any known biological activity, disease, or drug interactions. Pseudogenes are typically considered non-functional DNA sequences resulting from duplication or retrotransposition events and generally do not encode proteins or have a direct therapeutic relevance[2]. This entry is a pseudogene, not an active protein-coding gene, enzyme, receptor, or therapeutic target[2]. There is no evidence that MTND3P22 has a functional or pathological role, nor that it interacts with any drugs, serves as a biomarker, or is a safety concern. Information about the active MT-ND3 gene is available and related to mitochondrial disease, but MTND3P22 itself is non-functional[2][1]. If a therapeutic or diagnostic focus is intended, MTND3P22 is not an appropriate target.

Other names

MTND3P22mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 pseudogene 22